Haemorrhagic Thrombocythaemia

Christmas factor (IX) defect in a case of haemorrhagic thrombocythaemia.

The mechanism of bleeding in haemorrhagic thrombocythaemia is obscure. Although by definition there is always a raised platelet count, the haemorrhagic episodes cannot be satisfactorily correlated with the level of the count. In fact, thrombocythaemia can exist without bleeding manifestations (Fanger, Cella, and Litchman, 1954). The most commonly occurring laboratory defect is an abnormal bleed...

Headache in essential thrombocythaemia

Headache is frequently reported as one of the neurological manifestations of essential thrombocythaemia (ET) and other myeloproliferative neoplasms. It is associated with considerable morbidity; yet, it is a frequently under-recognised symptom. In patients with ET, headaches may be attributable to the disease, to the prescribed ET treatment, or unrelated to ET. The majority of headaches in ET a...

Primary thrombocythaemia following splenectomy.

Introduction Primary thrombocythaemia (PT) is a well recognized syndrome within the spectrum of myeloproliferative disorders. Typically presenting from middle-age onwards, difficulties may arise in differentiation from secondary thrombocytosis or other myeloproliferative states particularly in younger patients. This report of an unusual presentation ofPT in a 20-year-old male demonstrates some ...

Unrecognized pseudohyperkalaemia in essential thrombocythaemia

A 99-year-old woman was admitted following a mechanical fall. The patient suffered from frequent falls averaging around six falls per year. On this occasion the patient explained that she had simply lost her balance and denied any further symptoms. The patient’s past medical history was significant for essential thrombocythaemia diagnosed 10 years earlier which was initially managed with hydrox...

Migrating emboli of retinal arteries in thrombocythaemia.